Cores may be samples from different areas of the same tumor or different tumors in the prostate. Because the grade may vary within the same tumor or between different tumors, different samples (cores) taken from your prostate may have different Gleason Scores. Typically, the highest (largest number) Gleason Score will be the one used by your doctor for predicting your prognosis and deciding treatment. 

Early detection saved my life.  More men need to know about their risk, and their opportunities to get screened.

~ Keith Wegen, prostate cancer survivor

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