PCEC Research

In addition to screening millions of men, the Prostate Conditions Education Council (PCEC) participates in research and supports the development of technology to advance the detection and treatment of prostate cancer as well as other important men’s health conditions.

Current research focuses on data from our Prostate Cancer Awareness Week early detection program and the Know Your Numbers campaign.  These efforts include testing participants for PSA, Total Testosterone, Total Cholesterol, Glucose levels and the PCA3 (a urine prostate cancer biomarker). Based on our data and biorepositiory of serum, researchers have made groundbreaking advances, had presentations at national medical meetings and published hundreds of papers in leading medical journals.

Further our programs and data have proven critical in the recruitment of research participants and sites for many clinical trials.

PCEC is proud of our extensive database and serum biorepository and are honored to consider proposals for the usage of these monumental resources.

PCEC extends a special note of recognition and appreciation to Screening Sites who participate as Longitudinal Study Site Partners. The early detection events have helped PCEC and our Council physicians to advance research efforts on new and more sensitive biomarkers for prostate cancer.  It is our goal to continue to contribute to research and provide our unique services to finding improved detection methods, which eliminate unnecessary biopsies and help develop tools to determine aggressive from non-aggressive disease.

Randomized controlled screening trials for prostate cancer using prostate-speciWc antigen: a tale of contrasts

World J Urol DOI 10.1007/s00345-011-0799-4
Kyle O. Rove • E. David Crawford
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Validation of the modified American Urological Association symptom score

J Urol. 2011 Sep;186(3):945-8. Epub 2011 Jul 24.
Crawford ED, O'Donnell CI, Barqawi AB, O'Leary M, Sullivan KF, Hughes A, Roehrborn CG, Maroni P.
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Methods of developing UWIN, the modified American Urological Association symptom score

J Urol. 2011 Sep;186(3):940-4. Epub 2011 Jul 24.
Barqawi AB, Sullivan KF, Crawford ED, Roehrborn CG, Hughes A, O'Leary M, Stone N, O'Donnell CI.
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Prostate-specific antigen 1.5-4.0 ng/mL: a diagnostic challenge and danger zone

BJU Int. 2011 Dec;108(11):1743-9. doi: 10.1111/j.1464-410X.2011.10224.x. Epub 2011 Jun 28.
Crawford ED, Moul JW, Rove KO, Pettaway CA, Lamerato LE, Hughes A.
Access the full report here.

Effect of Statins on Serum Prostate-specific Antigen Levels

Urology. 2010 Nov;76(5):1048-51.
Akduman B, Tandberg DJ, O'Donnell CI, Hughes A, Moyad MA, Crawford ED.
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