Clinical Trials


A clinical research study for patients whose prostate cancer has not spread beyond the prostate is now enrolling. Aragon Pharmaceuticals is seeking men to participate in a clinical trial of an investigational drug for prostate cancer. The purpose of the SPARTAN study is to evaluate the safety and effectiveness of an investigational drug in delaying prostate cancer from spreading beyond the prostate.  This study is enrolling patients with prostate cancer who, despite treatment, have rising blood prostate-specific antigen (PSA) levels.  All participants will continue to receive their current treatment along with either the investigational medication or a placebo.  The selections will be random, and the investigational medication will be given to 2 out of every 3 study participants.
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ERA 223 Study

A clinicial research study for patients with asymptomatica/mildly symptomatic castration resistant prostate cancer and two or more bone metastases.  Bayer HealthCare is seeking men to participate in a research study of radium-223.  The purpose of the ERA 223 trial is to determine if the addition of radium-223 to abiraterone acetate is able to prolong life and to delay events specific for prostate cancer which has spread to the bone, such as bone fractures or bone pain which needs to be treated with an X-Ray machine.  This study is enrolling pateints with prostate cancer who, despite medical or surgical castration, have rising prostate specific antigen (PSA) levels. Eligible patients must have two or more bone metastases with no visceral, e.g. liver metastases and not have received prior chemotherapy.  Prostate cancer lesions must be asymptomatic or mildly symptomatic.  All patients will receive abiraterone acetate along with either radium-223 or placebo. 
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This Prosper Trial is a Phase 3, safety and efficacy study of Enzalutamide in patients with nonmetastatic castration-resistant prostate cancer.